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Publications

 

2011

Kuipers, A., Rink, R., Moll, G.N., (2011) Genetics, biosynthesis, structure and mode of action of lantibiotics. In: Prokaryotic antimicobial peptides, from genes to applications. Eds. D. Drider, S. Rebuffat. In press.

2010

Kuipers, A. (2010) Microbial production of thioether-stabilized peptides. Ph.D. Thesis. University of Groningen.

Plat, A., Kluskens, L.D., Kuipers, A., Rink, R., Moll, G.N., (2010) Requirements of the engineered leader peptide of nisin for inducing modification, export and cleavage. Appl. Environ. Microbiol. Epud ahead of print.

de Vries, L., Reitzema-Klein, C.E., Arkema , A., van Dam, D., Rink, R., Moll, G.N., Haas-Jimoh-Akanbi, M. (2010) Oral and pulmonary delivery of thioether-bridged angiotensin-(1-7). Peptides. 31:893-8.

Rink, R., Arkema-Meter, A., Baudoin, I., Post, E., Kuipers, A., Nelemans, S.A., Haas-Jimoh-Akanbi, M., Moll, G.N. (2010) To protect peptide pharmaceuticals against peptidases. J. Pharmacol. Toxicol. Methods. 61:210-8.

Moll, G.N., Kuipers, A., Rink, R., (2010) Microbial engineering of dehydro-amino acids and lanthionines in non-lantiobiotic peptides. Antonie van Leeuwenhoek. 97:319-33

Mahjchrzykiewics, J.A., Lubelski, J., Moll, G.N., Kuipers, A., Bijlsma, J.J., Kuipers, O.P., RInk, R. (2010) Production of a calss II two-component lantibiotic of Streptococcus pneumoniae using the class I nisin synthetic machinery and leader sequence. Antimicrob. Agents Chemother. 54:1498-505.

 

2009

Kuipers, A., Rink, R., Moll, G. N. (2009) Translocation of a thioether-bridged azurin peptide fragment via the sec pathway in Lactococcus lactis. Appl. Environ. Microbiol. 75:3800-3802.

Kluskens, L. D., Nelemans, S. A., Rink, R., de Vries, L., Meter-Arkema, A., Wang, Y., Walther, T., Kuipers, A., Moll, G. N., Haas, M. (2009) Angiotensin-(1-7) with thioether bridge: an angiotensin-converting enzyme-resistant, potent angiotensin-(1-7) analog. J. Pharmacol. Exp. Ther. 328:849-854.

 

Moll, G. N., Kuipers, A., de Vries, L., Bosma, T., and Rink, R. (2009) A biological stabilization technology for peptide drugs: enzymatic introduction of thioether-bridges. Drug Discovery Today Technologies. doi:10.1016/j.ddtec.2009.03.001.

 

 

2008

Robillard. G.T., Scholtmeijer, K., Hass, M. and Smisterova, J. 2008, Can nanotechnology improve the oral delivery of therapeutic proteins? In Towards Drugs of the Future: Key issues in lead finding and lead optimisation (ed. C.G. Kruse & H. Timmerman, IOP Press, Amsterdam)

Kuipers, A., Meijer-Wierenga, J., Rink, R., Kluskens, L.D., Moll, G.N. 2008. Mechanistic dissection of the enzyme complexes involved in the biosynthesis of lacticin 3147 and nisin. Appl. Environ. Microbiol 74 6591-7

Lubelski, J., Overkamp, W., Kluskens, L.D., Moll, G.N. and Kuipers, O.P. 2008. The influence of shifting positions of Ser, Thr and Cys residues in prenisin on the efficiency of modification reactions and on the antimicrobial activity of the modified propeptides. Appl. Environ. Microbiol. 74: 4680-4685

Lubelski, J., Rink, R., Khusainov, R., Moll, G.N., and Kuipers, O.P. 2008. Biosynthesis, immunity, regulation, mode of action and engineering of the model lantibiotic nisin. Cell. Mol. Life Sci. 65: 455-476.

Dudia, A., Koçer, A., Subramaniam, V., Kanger, J. S.  2008,  Biofunctionalized Lipid-Polymer Hybrid Nanocontainers with Controlled Permeability  Nano Lett.; ASAP Article;  DOI: 10.1021/nl073211b

El Khattabi, M., Van Roosmalen, M.L., Jager, D., Metselaar, H., Permentier,H.,  Leenhouts, K., and Broos. J., 2008. Lactococcus lactis as expression host for the biosynthetic incorporation of tryptophan analogues in recombinant proteins. Biochemical Journal, 409, 193-8

Van den Berg van Saparoea, H.B., Bakkes, P.J., Moll, G.N. and Driessen, A.J.M. 2008. Distinct contributions of the nisin biosynthesis enzymes NisB, NisC and the transporter NisT in prenisin production by Lactococcus lactis. Appl. Environ. Microbiol. 74, 5541-8

 

2007

Bijker, W.E., de Beaufort, I.E., van den Berg, A., Borm, P.J.A., Oyen, W.J.G., Robillard, G.T., van Dijk, H.F.G. 2007 "A response to 'Nanotechnology and the need for risk governance' O. Renn & M.C. Roco 2006. J. Nanoparticle Research 8(2): 152-199" J. Nanopart. Res. 9 1217-1220

Koçer, A.  2007  A Remote Controlled Valve in Liposomes for Triggered Liposomal Release  J Liposome Research 17, 219-225

Corvis, Y., Trzcinska, K., Rink, R., Bilkova, P., Gorecka, E., Bilewicz, R., Rogalska, E. 2007, Electron-donor-acceptor fullerene deivative retained on electrodes using SC3 Hydrophobin, J. Phys. Chem C 111, 1176-1179

Shi, F., Gounko, N.V., Wang, X., Ronken, E., Hoekstra, D. 2007, In situ entry of oligonucleotides into brain cells can occur through a nucleic acid channel Oligonucleotides 17: 122-133

Zuhorn, I.S., Kalicharan, D., Robillard, G.T., Hoekstra, D. 2007 Adhesion receptors mediate efficient non-viral gene delivery. Mol. Therapy 15: 946-953

Rink, R., Wierenga, J., Kuipers, A., Kluskens, L.D., Driessen, A.J., Kuipers, O.P., Moll, G.N. 2007 Production of dehydroamino acid-containing peptides by Lactococcus lactis. Appl Environ Microbiol. 73:1792-1796 

Koçer, A., Walko, M. and Feringa, B.L. 2007  Synthesis and Utilization of reversible and irreversible light-activated nanovalves derived from the channel protein MscL  Nature Protocols, 2, 1426-1437.

Rink, R., Wierenga, J., Kuipers, A., Kluskens, L. D., Driessen, A. J. M., Kuipers, O. P. and Moll, G. N. 2007  Dissection and moculation of the four distinct activities of nisin by mutagensis of rings A and B and by C-terminal tuncation Appl. Environ. Microbiol. 73 5809-5816.

http://www.f1000biology.com/article/id/1090599, http://www.asm.org/microbe/index.asp?bid=53952,

 Rink, R., Kluskens, L. D., Kuipers, A., Driessen, A. J. M., Kuipers, O. P. and Moll, G. N. (2007) NisC, the cyclase of the lantibiotic nisin, can catalyze cyclization of designed non-lantibiotic peptides. Biochemistry 46, 13179-13189

Miedema, H., M. Vrouenraets, J. Wierenga, W. Meijberg, G. Robillard, B. Eisenberg  2007. A biological porin engineerded into a molecular, nanofluidic diode. Nano Lett., 7: 2886-2891.

Wösten, H.A.B., Scholtmeijer, K. and de Vries, R.P. 2007. Hyper production of enzymes by fungi. In press.

El Khattabi, M., Van Roosmalen, M.L., Jager, D., Metselaar, H., Permentier,H.,  Leenhouts, K., and Broos. J., 2007. Lactococcus lactis as expression host for the biosynthetic incorporation of tryptophan analogues in recombinant proteins. Biochemical Journal. In press.

 

2006

Sardone, L., V. Palermo, E. Devaux, D. Credgington, M. de Loos, G. Marletta, F. Cacialli, J. van Esch, P. Samori. 2006. Electric-field-assisted alignment of supramolecular fibers. Advanced Materials 18: 1276-1280.

R. Ramasamy, S. Yasawardena,  A. Zomer, G. Venema, J. Kok, K. Leenhouts. 2006. Immunogenicity of a malaria parasite antigen displayed by Lactococcus lactis in oral immunisations. Vaccine 24:3900-3908

Audouy, S.A.L., Roosmalen, M.L. van, Neef, J., Kanninga, R., Deemter, M. van, Selm, S. van, Robillard, G.T., Leenhouts, C.J., Hermans, P.W.M. 2006. Lactococcus lactis GEM particles displaying pneumococcal antigens induce local and systemic immune responses following intranasal immunization. Vaccine.24:5434-5441

Miedema, H., M. Vrouenraets, J. Wierenga, B. Eisenberg, D. Gillespie, W. Meijberg, W. Nonner. 2006. Ca2+ selectivity of a chemically modified OmpF with reduced pore volume. Biophys. J., 91: 4392-4400.

Miedema, H., Wierenga, J., Vrouenraets, M., Schirmer, T., Eisenberg, B., Basle, A., Meijberg, W. 2006  Conductance and selectivity fluctuations in D127 mutants of the bacterial porin OmpF. Eur. J. Biophys., 36: 13-22.

Kocer, A., Walko, M., Bulten, E., Halza, E., Feringa, B.L., Meijberg, W. 2006. Rationally designed chemical modulators convert a bacterial channel protein into a pH-sensory valve. Angew. Chem. Int. Ed..45: 3126-3130

Askolin, S., Linder, Scholtmeijer, K., Tenkanen, M., Penttilä, M., de Vocht, M.L., Wösten, H.A.B. 2006. The class II hydrophobins HFBI and HBII of Trichoderma reesei have distinct assembly characteristics at hydrophilic-hydrophobic interfaces. Biomacromolecules 7: 1295-1301.

Audouy, S.A.L., Roosmalen, M.L. van, Neef, J., Kanninga, R., Deemter, M. van, Selm, S. van, Robillard, G.T., Leenhouts, K.J., Hermans, P.W.M. 2006. Lactococcus lactis GEM particles displaying pneumococcal antigens induce local and systemic immune responses following intranasal immunization. Vaccine 24:5434-5441.

Bosma, T., Kanninga, R., Neef, J., Audouy, S.A.L., Roosmalen, M.L. van, Steen, A., Buist, G., Kok, J., Kuipers, O.P., Robillard, G.T., Leenhouts, C.J. 2006. A novel surface display system for proteins on non-genetically modified Gram-positive bacteria. Appl. Environ. Microbiol.  72: 880-889.

Corvis, Y., van der Heyden A., Mutelet, F., Brezesinski G., Rink, R. and Rogalska, E. 2006 Adaptive interactions of SC3 hydrophobin with model lipid membranes. Anal. Chem. 78: 4850-4864.

Corvis, Y., Trzcinska, K., Rink R., Bilkova, P., Gorecka, E., Bilewicz, R. and Rogalska, E. 2006. An electron donor-acceptor fullerence derivate retained on electrodes using SC3 hydrophobin. Chem. comm. Submitted.

Fan, H., Wang, X., Zhu, J., Robillard, G.T., Mark, A.E. 2006. Molecular Dynamics Simulations of the Hydrophobin SC3 at a Hydrophobic/Hydrophilic Interface. Proteins: Structure, Function, and Bioinformatics 64: 863-873.

Li B., Yu J.P.J., Brunzelle J.S., Moll G.N., Donk W.A. van der, Nair S.K., 2006, Structure and Mechanism of the Lantibiotic Cyclase Involved in Nisin Biosynthesis. Science. 311: 1464-1467.   

Montalti, M., Dolci, L.S., Prodi, L., Zaccheroni, N., Stuart, M.C.A., van Bommel, K.J.C, Friggeri, A. 2006. Energy transfer from a fluorescent hydrogel to a hosted fluorophore. Langmuir. 22: 2299-2303.

Roosmalen, M.L. van, Kanninga, R., El Khattabi, M., Neef, J., Audouy, S., Bosma, T., Kuipers, A., Post, E., Steen, A., Kok, J., Buist, G., Kuipers, O.P., Robillard, G.T., Leenhouts, C.J.. 2006. Mucosal vaccine delivery of antigens tightly bound to an adjuvant particle made from food-grade bacteria. Methods 38:144-149. 

Vrouenraets, M. Wierenga, J., Meijberg, W. Miedema, H. 2006 Chemical modification of the bacterial Porin OmpF: Gain of selectivity by volume reduction. Biophys J. 90, 1202-1211

Kuipers, A., Wierenga, J., Rink, R., Kluskens, L.D., Driessen, A.J.M., Kuipers O.P., and Moll, G.N. 2006. Sec-Mediated Transport of Post-Translationally Dehydrated Peptides in Lactococcus lactis. Appl. Environ. Microbiol. 72: 7626-7633

 

2005

Van Bommel, K. J. C., M. C. A. Stuart, B. L. Feringa, and J. van Esch. 2005. Two-stage enzyme mediated drug release from LMWG hydrogels. Organic and Biomolecular Chemistry 3: 2917-2920

Van Bommel, K. J. C., A. Friggeri, M. C. A. Stuart, B. L. Feringa, and J. van Esch. 2005. Protecting substrates from enzymatic cleavage: hydrogels of low molecular weight gelators do the trick. Journal of Controlled Release 101: 287–290

Corvis, Y., A. Walcarius, R. Rink, N. T. Mrabet, and E. Rogalska. 2005. Preparing Catalytic Surfaces for Sensing Applications by Immobilizing Enzymes via Hydrophobin Layers. Anal. Chem. 77: 1622-1630.

Friggeri, A., van Bommel, K.J.C., Shinkai, S. 2005. Molecular Gels. Materials with Self-Assembled Fibrillar Networks. R. G. Weiss and P. Terech (eds.). 25: 853–889. Springer Publishers.

Friggeri, A., C. van der Pol, K. J. C. van Bommel, A. Heeres, M. A. Stuart, B. L. Feringa, J. van Esch. 2005. Cyclohexane-based low molecular weight hydrogelators: a chirality investigation, Chem. Eur. J., 11: 5353 – 5361.

Friggeri, A., K. J. C. van Bommel, M. de Jong, C. van der Pol, and J. van Esch.  2005. A New Class of Gelators: Exploring the Compatibility in Cosmetics. Cosmetics & Toiletries 120: 67-76.

Hektor, H. J. and K. Scholtmeijer. 2005. Hydrophobins: proteins with potential. Current Opinion in Biotechnology 16: 434-439

Jeong, Y., A. Friggeri, I. Akiba, H. Masunaga, K. Sakurai, S. Sakurai, S. Okamoto, K. Inoue, and S. Shinkai. 2005. Small-angle X-ray scattering from a dual-component organogel to exhibit a charge transfer interaction. Journal of Colloid and Interface Science 283: 113–122.

De Loos, M., A. Friggeri, J. van Esch, R. M. Kellogg, and B. L. Feringa. 2005. Cyclohexane bis-urea compounds for the gelation of water. Organic and Biomolecular Chemistry 3: 1631–1639.

Kocer, A., Walko, M., Meijberg W., Feringa B.L. 2005. A light-actuated nanovalve derived from a channel protein. Science 309, 755-758

Kluskens L.D.,  A. Kuipers, R. Rink, E. de Boef, S. Fekken, A.J.M. Driessen, O.P. Kuipers and G.N. Moll. 2005. Post-translational Modification of Therapeutic Peptides By NisB, the Dehydratase of the Lantibiotic Nisin. Biochemistry, 44, 12827-12834

Rink R., A. Kuipers, E. de Boef, C.J. Leenhouts, A.J. M. Driessen, G.N. Moll and O.P. Kuipers. 2005. Lantibiotic Structures as Guidelines for the Design of Peptides That Can Be Modified by Lantibiotic Enzymes. Biochemistry, 44, 8873-8882

Scholtmeijer, K., R. Rink, H. J. Hektor, and H. A. B. Wösten. 2005. Expression and Engineering of Fungal Hydrophobins. Applied Mycology and Biotechnology. An International Elsevier Series, Volume 5 & 6 Fungal Genomics & Bioinformatics

Wang, X., F. Shi, H. A. B. Wösten, H. Hektor, B. Poolman, and G. T. Robillard. 2005. The SC3 Hydrophobin Self-Assembles into a Membrane with Distinct Mass Transfer Properties. Biophys. J. 88: 3434-3443.

 

2004

Allen, S. J., A. R. Curran, R. H. Templer, W. Meijberg, and P. J.  Booth. 2004. Folding Kinetics of an α Helical Membrane Protein in Phospholipid Bilayer Vesicles. J. Mol. Biol. 342: 1279-1291.

Allen, S. J., A. R. Curran, R. H. Templer, W. Meijberg, and P. J.  Booth. 2004. Controlling the Folding Efficiency of an Integral Membrane Protein J. Mol. Biol. 342: 1293-1304.

Alves, A.M.C.R., Record, E., Lomascolo, A., Scholtmeijer, K., Asther, M., Wessels, J.G.J., Wösten, H.A.B. 2004. Highly Efficient Production of Laccase by the Basidiomycete Pycnoporus cinnabarinus. Applied Environ. Microbiol. 70: 6379-6384.  

van Bommel, K. J. C., C. van der Pol, I. Muizebelt, A. Friggeri, A. Heeres, A. Meetsma, B. L. Feringa, and J. van Esch. 2004. Responsive cyclohexane-based low-molecular-weight hydrogelators with modular architecture. Angewandte Chemie 116:1695-1699.

Bulle-Lieuwma, C. W. T., J. K. J. van Duren, X. Yang, J. Loos, A. B. Sieval, J. C. Hummelen, and R. A. J. Janssen. 2004. Characterization of poly(p-phenylene vinylene)/methanofullerene blends of polymer solar cells by time-of-flight secondary ion mass spectrometry. Applied Surface Science 231-2:274-277.

van Dongen, G. A. M. S., G. W. Visser, and M. B. Vrouenraets. 2004. Photosensitizer-antibody conjugates for detection and therapy of cancer. Advanced Drug Delivery Reviews 56:31-52.

Friggeri, A., B. L. Feringa, and J. van Esch. 2004. Entrapment and release of quinoline derivatives using a hydrogel of a low molecular weight gelator. J.Contr.Rel. 97:241-248.

Hulst, R., I. Muizebelt, P. Oosting, C. van der Pol, A. Wagenaar, J. Šmisterová, E. Bulten, C. Driessen, D. Hoekstra, and J. B. F. N. Engberts. 2004. Sunfish amphiphiles: Conceptually new carriers for DNA delivery. European Journal of Organic Chemistry 835-849.  

Kuipers, A., E. de Boef, R. Rink, S. Fekken, L. D. Kluskens, A. J. M. Driessen, K. Leenhouts, O. P. Kuipers, and G. N. Moll. 2004. NisT, the transporter of the lantibiotic nisin, can transport fully modified, dehydrated, and unmodified prenisin and fusions of the leader peptide with non-lantibiotic peptides. J.Biol.Chem. 279:22176-22182.

Miedema, H., A. Meter-Arkema, J. Wierenga, H. Hektor, J. Tang, B. Eisenberg, and W. Meijberg. 2004. Permeation properties of an engineered OmpF containing the EEEE locus of Ca-channels. Biophysical J. 87: 3137-3147.  

van Roosmalen, M. L., N. Geukens, J. D. H. Jongbloed, H. Tjalsma, J. Y. Dubois, S. Bron, J. M. van Dijl, J. Anne.  2004. Type I signal peptidases of Gram-positive bacteria. BBA - Molecular Cell Research 1694: 279-297.

Scholtmeijer, K., M. I. Janssen, M. B. M. van Leeuwen, T. G.  van Kooten, H. Hektor, and H. A. B.  Wösten. 2004. The use of hydrophobins to functionalize surfaces. Bio-Medical Materials and Engineering 14: 447-454.

Wang, X. Q., J. F. Graveland-Bikker, C. G. De Kruif, and G. T. Robillard. 2004. Oligomerization of hydrophobin SC3 in solution: From soluble state to self-assembly. Protein Sci. 13: 810-821.

Wang, X. Q., H. P. Permentier, R. Rink, J. A. Kruijtzer, R. M. Liskamp, H. A. Wösten, B. Poolman, and G. T. Robillard. 2004. Probing the Self-Assembly and the Accompanying Structural Changes of Hydrophobin SC3 on a Hydrophobic Surface by Mass Spectrometry. Biophys. J. 87:1919-1928.

 

2003

van Bommel, K.J.C., A. Friggeri, and S. Shinkai. 2003. Organic Templates for the Fabrication of Inorganic Materials, Angewandte Chemie 115: 1010-1030.

Egelhaaf, S. U., E. van Swieten, T. Bosma, E. de Boef, A. A. van Dijk, and G. T. Robillard. 2003. Size and shape of the repetitive domain of high molecular weight wheat gluten proteins. 1. Small angle neutron scattering. Biopolymers 69:311-324.

Haas, M., E de Boer, P. E. de Jong, F. Moolenaar, D. K. F.  Meijer, D. de Zeeuw. 2003. Effects of anti-proteinuric therapy with angiotensin-converting-enzyme inhibition on renal protein catabolism in the adriamycin-induced nephrotic rat. Clinical Science 105: 51-57.

Heeres, A., C. van der Pol, M. Stuart, A. Friggeri, B. L. Feringa, and J. van Esch. 2003. Orthogonal self-assembly of low molecular weight hydrogelators and surfactants. Journal of the American Chemical Society 125:14252-14253.

Kuipers, O. P.,  C. J. Leenhouts. 2003. Regulation of gene expression in Lactococcus lactis. In: The Lactic Acid Bacteria. Vol. 3: Genetics of Lactic Acid Bacteria (Eds. BJB Wood, PJ Warner), 121-142. Kluwer Academic/Plenum Publishers, New York.

Miedema, H., A. H. de Boer, and O. Pantoja. 2003. The gating kinetics of the slow vacuolar channel. A novel mechanism for SV channel functioning? Journal of Membrane Biology 194:11-20.

Pijper, D., E. Bulten, J. Šmisterová, A. Wagenaar, D. Hoekstra, J. B. F. N. Engberts, and R. Hulst. 2003. Novel biodegradable pyridinium amphiphiles for gene delivery. European Journal of Organic Chemistry 22: 4406-4412.

Steen, A., G. Buist, K. J. Leenhouts, M. El Khattabi, F. Grijpstra, A. L. Zomer, G. Venema, O. P. Kuipers, and J. Kok. 2003. Cell wall attachment of a widely distributed peptidoglycan binding domain is hindered by cell wall constituents. J.Biol.Chem. 278:23874-23881.

van Swieten, E., R. H. E. Friesen, C. G. De Kruif, and G. T. Robillard. 2003. Size and shape of the repetitive domain of high molecular weight wheat gluten proteins. II. Hydrodynamic studies. Biopolymers 69:325-332.

Venema, R., H. Tjalsma, J.M. van Dijl, A. de Jong, K. Leenhouts, G. Buist, and G. Venema 2003. Active Lipoprotein Precursors in the Gram-positive Eubacterium Lactococcus lactis. J. Biol. Chem. 278: 14739-14746.

 

2002

Scholtmeijer, K. and H. A. B. Wösten. 2002. Intron-dependent mRNA accumulation in filamentous fungi. Recent Research Developments in Molecular Microbiology 1: 105-117

Campo, N., M. L. Davaran-Mingot, K. Leenhouts, P. Ritzenthaler, and P. Le Bourgeois. 2002. A Cre/loxP recombination system for large genome rearrangements in Lactococcus lactis. Appl. Environ. Microbiol. 68: 2359-2367.

Friggeri, A.,  O. Gronwald, K. J. C. van Bommel, S. Shinkai, and D. N. Reinhoudt. 2002. Charge-transfer phenomena in novel, dual-component, sugar-based organogels, J. Am. Chem. Soc. 124: 10754-10758.

Haas, M., F. Moolenaar, A. Elsinga, E. A. van der Wouden, P. E. de Jong, D. K. F. Meijer, and D. de Zeeuw. 2002. Targeting of doxorubicin to the urinary bladder of the rat shows increased cytotoxicity in the bladder urine combined with an absence of renal toxicity. J. of Drug Targeting 10: 81-89.

Haas, M., F. Moolenaar, D. K. F. Meijer, and D. de Zeeuw. 2002. Symposium: Renal aspects of cardiovascular pharmacotherapy: specific drug delivery to the kidney. Cardiovascular Drugs and Therapy 16: 489-496.

Heuberger, E.H.M.L., L. M. Veenhoff, R. H. Duurkens, R. H. E. Friesen, and B. Poolman. 2002. Oligomeric state of membrane transport proteins analyzed with blue native electrophoresis and analytical ultracentrifugation. Journal of Molecular Biology 317: 591-600.

Janssen, M.I., M. B. M. van Leeuwen, K. Scholtmeijer, T. G. van Kooten, L. Dijkhuizen, and H. A. B. Wösten. 2002. Coating with genetic engineered hydrophobin promotes growth of fibroblasts on a hydrophobic solid. Biomaterials 23: 4847-4854.

Meijberg, W. and P. J. Booth. 2002. The activation energy for insertion of transmembrane alpha-helices is dependent on membrane composition. J. Mol. Biol. 319:839-853.

Poolman, B., P. Blount, J. Folgering, R. H. E. Friesen, P. C. Moe, and T. van der Heide. 2002 How do membrane proteins sense water stress? Molecular Microbiology 44: 889-902.

Roosjen, A., J. Šmisterová, C. Driessen, J. T. Anders, A. Wagenaar, R. Hulst, D. Hoekstra, and J. B. F. N. Engberts. 2002. Synthesis and characterization of degradable pyridinium transfection agents, Eur. J. Org. Chem. 7: 1721

Scholtmeijer, K., M. I. Janssen, B. Gerssen, M. L. de Vocht, B. M. van Leeuwen, T. G, van Kooten, H. A. B. Wösten, and J. G. H. Wessels. 2002. Surface modifications using engineered hydrophobins. Appl. and Environmental Microbiol. 68:1367-1373.

Serrano, P. J. M., J. P. M. van Duynhoven, R. J. Gaymans, and R. Hulst. 2002. Morphology of alternating poly(ester amide)s based on 1,4-butylene established by C-13 solid-state NMR relaxation measurements. Macromolecules 35:8013-8019. 

de Vocht, M.L., I. Reviakine, W-P. Ulrich, W. Bergsma-Schutter, H. A. B. Wösten, H. Vogel, A. Brisson, J. G. H. Wessels, and G. T. Robillard. 2002. Self-assembly of the hydrophobin SC3 proceeds via two structural intermediates. Protein Science 11: 1199-1205.

Wang X., M. L. de Vocht, J. de Jonge, B. Poolman, and G.T. Robillard 2002. Structural changes and molecular interactions of hydrophobin SC3 in solution and on a hydrophobic surface. Protein science 11: 1172-1181.

Zangi, R., M. L. de Vocht, G. T. Robillard, and A. E. Mark. 2002. Molecular dynamics study of the folding of hydrophobin SC3 at a hydrophilic/hydrophobic interface. Biophysical journal 83:112-124.

Zuhorn, I. S., V. Oberle, W. H. Visser, J. B. F. N. Engberts, U. Bakowsky, E. Polushkin, and D. Hoekstra. 2002. Phase behavior of cationic amphiphiles and their mixtures with helper lipid influences lipoplex shape, DNA translocation, and transfection efficiency. Biophysical journal 83:2096-2108.

 

2001

Booth, P. J., R. H. Templer, W. Meijberg, S. J.  Allen, A. R. Curran, and M. Lorch. 2001. In vitro studies of membrane protein folding. Critical Reviews of Biochemistry and Molecular Biology 36 501-603.

Creveld, L. D., W. Meijberg, H. J. C. Berendsen, and H. A. M. Pepermans. 2001. DSC studies of Fusarium solani pisi cutinase: consequences for stability in the presence of surfactants. Biophysical Chemistry 92:65-75.

Haas, M., Y. Kato, R. F. G. Haverdings, F. Moolenaar, K. Suzuki, D. de Zeeuw, Y. Sugiyama, D. K. F. Meijer. 2001. Chapter 5: Delivery of drugs and antisense oligonucleotides to the proximal tubular cell of the kidney using macromolecular and prodrug approaches. In: G. Molema, D. K. F. Meijer (eds) Drug targeting: organ-specific strategies pp. 121-155, Wiley-VHC, Weinheim, Germany.

Haverdings, R. F. G., M. Haas, A. R. Greupink, P. A. de Vries, F. Moolenaar, D. de Zeeuw, D. K. F. Meijer. 2001. Possibilities and limitations of the low-molecular-weight protein lysozyme as a carrier for renal drug targeting. Renal Failure 23: 397-409.

Haverdings, R. F. G.,  R. J. Kok, M. Haas, F. Moolenaar, D. K. F. Meijer. 2001. Chapter 44: Drug Targeting to the Kidney: The Low-Molecular-Weight Protein Approach. In: S. Dumitriu (ed) Polymeric biomaterials pp. 1117-1140, Marcel Dekker, Inc., New York, United States.

Kuiper, J. M., R. T. Buwalda, R. Hulst, and J. B. F. N. Engberts. 2001. Novel pyridinium surfactants with unsaturated alkyl chains: Aggregation behavior and interactions with methyl orange in aqueous solution. Langmuir 17:5216-5224.

Scholtmeijer, K., J. G. H. Wessels, and H. A. B. Wösten. 2001. Fungal hydrophobins in medical and technical applications. Applied Microbiology and Biotechnology 56:1-8.

Scholtmeijer, K., H. A. B. Wösten, J. Springer, and J. G. H. Wessels.  2001. Effect of introns and AT-rich sequences on expression of the bacterial hygromycin B resistance gene in the basidiomycete Schizophyllum commune. Appl. and Environmental Microbiol. 67: 481-483.

Šmisterová, J., A. Wagenaar, M.C.A. Stuart, E. Polushkin, G. ten Brinke, R. Hulst, J.B.F.N. Engberts, and D. Hoekstra. 2001. Molecular shape of the cationic lipid controls the structure of the cationic lipid/dioleylphosphatidylethanolamine-DNA complexes and the efficiency of gene delivery, J. Biol.Chem. 276: 47615

Stamps, J. P., B. Ottink, J. M. Visser, J. P. M. van Duynhoven, and R. Hulst. 2001. Difftrain: A novel approach to a true spectroscopic single-scan diffusion measurement. Journal of Magnetic Resonance 151:28-31.

 



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